Henry Yelkin Glenn Goodwin Jonghoon Chang McHenry Mauger Erin Marra
HCA Healthcare
01-01-2023
Background: Effective evaluation of stroke symptoms necessitates a comprehensive clinical assessment, influencing the timely administration of tissue plasminogen activator (tPA). This study examines t..
Background: Effective evaluation of stroke symptoms necessitates a comprehensive clinical assessment, influencing the timely administration of tissue plasminogen activator (tPA). This study examines the relationship between patients’ preferred language as well demographic factors and stroke care metrics within the framework of the HCA Healthcare System. Methods: A retrospective study design was used to examine the national HCA database for all patients admitted to an HCA hospital with a diagnosis of stroke and with a recorded NIH stroke scale (NIHSS) between the years of 2017 and 2022. 37,956 patient visits from 170 HCA hospitals were analyzed to compare stroke metrics including tPA administration times (as measured from the arrival time of the patient in the emergency department (ED) to the time the tPA was administered), time to brain CT (as measured from the arrival time of the patient in the ED to the initiation time of the CT scan), NIHSS and hospital length of stay (LOS). We also evaluated whether demographic factors and language spoken affected the tPA administration rates among stroke patients. Results: tPA administration rates were affected by sex, ethnicity, age and insurance status. Hispanics were slightly more likely to get tPA than non-hispanics (8.7% vs 7.8%, p85: 7.5%, p Conclusions: The results of this retrospective study suggest there are differences in stroke management based on sex, ethnicity, race, age and insurance status. Most notably, men, Hispanics, younger aged patients and those with private insurance were the most likely to get tPa when presenting to the hospital with a stroke. Despite those differences, time to tPa was not impacted by any of the studied demographic factors. Language did not impact tPa administration rates, tPa administration times or the time to CT brain. Further research should be aimed to determine the reason behind these demographic differences in tPA administration rates as well as hospital LOS. Larger scale prospective studies should also be conducted to further stratify patients into specific preferred languages.