Abstract: Chronic limb-threatening ischemia (CLTI) is a serious condition that can lead to amputation and even death. Open and endovascular revascularization are two common treatment options for CLTI,..
Abstract: Chronic limb-threatening ischemia (CLTI) is a serious condition that can lead to amputation and even death. Open and endovascular revascularization are two common treatment options for CLTI, but the optimal treatment approach remains controversial. This study compared the 30-Day outcomes of open and endovascular revascularization using data from the National Surgical Quality Improvement Program (NSQIP) database. The study included 6,780 patients who underwent open bypass with saphenous vein, 4,201 patients who underwent open bypass with alternative conduit, and 8,887 patients who underwent endovascular intervention. Compared to open bypass with saphenous vein, endovascular intervention was associated with a higher rate of major amputation (1.4% vs. 1.0%, p=0.002) and major adverse limb events (MALE, 2.8% vs. 2.1%, p=0.004). However, endovascular intervention was also associated with a lower rate of major adverse cardiovascular events (MACE, 1.6% vs. 3.5%, p Conclusion: This study provides valuable insights into the 30-Day outcomes of open versus endovascular revascularization for CLTI. The findings suggest that endovascular intervention may be a safe and effective treatment option for selected patients, but careful patient selection is essential.
