HCA Healthcare Graduate Medical Education 2024 Research Days
A Retrospective Study on the Effect of RAAS Pathway Inhibitors at Decreasing the Risk of Acute Coronary Syndrome in Hypertensive Patients with Rheumatoid Arthritis as Compared to Other Antihypertensives
Rheumatoid arthritis (RA) is a chronic multi-system inflammatory disease of which is characterized by articular and extra-articular involvement. Patients with RA have a higher risk of mortality when c..
Rheumatoid arthritis (RA) is a chronic multi-system inflammatory disease of which is characterized by articular and extra-articular involvement. Patients with RA have a higher risk of mortality when compared with the general population, which is due predominantly to increased cardiovascular disease. Due to the higher incidence of CVD and MI in RA patients it has been postulated that enhanced systemic inflammation plays an important role in the pathogenesis of CVD in RA patients. Previous studies have shown that ant inflammatory medication such as systemic steroids and immune blockers have been shown to decrease the risk of MI in patients with rheumatoid arthritis. Our results found that there was a decrease in the risk of ACS In patients taking ace inhibitors however the p value was not sustain due to a lack of sample size.
