Surgical Management of Necrotic Wounds Following Rituximab Therapyfor Waldenstrom’s Macroglobulinemia: A Case Report
Ocala Regional Medical Center
Waldenstrom’s Macroglobulinemia, Non Hodgkin Lymphoma, Pediatric Ovarian Cancer, Skin Necrosis, Calciphylaxis, Monoclonal Antibody Therapy
Internal Medicine | Neoplasms | Oncology | Skin and Connective Tissue Diseases
We report the case of a 77-year-old woman who developed extensive necrosis of the skin and subcutaneous tissue of bilateral lower extremities following administration of Rituximab antibody therapy for Waldenstrom’s macroglobulinemia. The morphology and presentation of these lesions may represent calciphylaxis, a rare life- threatening disease characterized by soft tissue necrosis. We wish to inform the medical community of the potential for developing this rare condition in patients, especially those with concomitant risk factors, undergoing antibody therapy interventions.
Publisher or Conference
Journal of Case Reports in Cancer
Lockart K, Quinto E, Ferber L. Surgical Management of Necrotic Wounds Following Rituximab Therapy for Waldenstrom’s Macroglobulinemia: A Case Report. J Case Reports Cancer. 2020;1(1):105. doi: https://doi.org/10.33790/jcrc1100105