Bleeding Risk with Rivaroxaban, Enoxaparin, and Aspirin Following Total Joint Arthroplasty or Revision
Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is a potentially fatal byt preventable complication of orthopedic surgery. Following surgery, patients are routinely started on prophylactic oral or pareteral anticoagulation. Standard medicaions used in this setting include enoxaparin, low-dose ungractionated heparin, vitamin K antagonists, fondaparinux, apixaban, dabigatran, rivaroxaban, and aspirin. A major risk when using these medications is bleeding and must be considered when choosing among them.