Title

Ethacrynic Acid

Division

Far West

Hospital

Riverside

Document Type

Review Article

Publication Date

6-9-2020

Keywords

diuretics, edema, heart failure, renal insufficiency

Disciplines

Cardiology | Chemicals and Drugs | Emergency Medicine | Organic Chemicals

Abstract

Excerpt

Ethacrynic acid is a loop diuretic that gained FDA approval for widespread use in 1967. Unlike other loop diuretics, ethacrynic acid is a novel drug due to the absence of a sulfonamide group in its structure, allowing its use in critically ill patients with life-threatening sulfa-allergies.[1] In adults, ethacrynic acid is a choice for the relief of edema in patients with renal failure, congestive heart failure, and cirrhotic ascites in the setting of sulfonamide hypersensitivity and treatment-resistant pathologies.

Publisher or Conference

StatPearls

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