The Statewide Epidemiology of Mucormycosis Among Trauma Patients in Florida.
Ocala Regional Medical Center
infection, mucormycosis, trauma acute care
Bacterial Infections and Mycoses | Surgery | Trauma
OBJECTIVES: Mucormycosis is a rare angioinvasive infection caused by filamentous fungi with a high lethality among the immunocompromised. In healthy people, the innate immune system is sufficient to prevent infection. The exception to this is deep tissue exposure seen during trauma. The purpose of this study is to evaluate the epidemiology of mucormycosis using a statewide population-based data set.
METHODS: This is a retrospective cohort study of all hospital admissions for mucormycosis within the state of Florida from 1997 through the beginning of 2020. A distribution map was created to evaluate for geographic variation. Botanical growth zones, based on plant hardiness, used by state environmental agencies and landscapers were also used to detect possible patterns based on climate conditions throughout Florida. A multivariable regression analysis was performed to account for confounders and limit bias.
RESULTS: A total of 1190 patients were identified for mucormycosis infection. Only 86 of these patients were admitted for trauma. Cutaneous infections were more prevalent among trauma patients while non-trauma patients had more pulmonary infections (
CONCLUSION: Trauma patients who develop infection from mucormycosis are at high risk of death despite being a younger and healthier population. Mucormycosis infections were primarily soft tissue based among trauma patients. These infections are more prevalent in colder regions within Florida.
Publisher or Conference
The American Surgeon
Clark JM, Liu H, Collins S, et al. The Statewide Epidemiology of Mucormycosis Among Trauma Patients in Florida [published online ahead of print, 2021 Oct 13]. Am Surg. 2021;31348211050576. doi:10.1177/00031348211050576