Third-Degree Heart Block Associated With Saddle Pulmonary Embolism: A Rare Sequelae of COVID-19-Induced Hypercoagulable State
North Florida Regional Medical Center
covid 19, hypercoagulable state, third degree atrioventricular block, pulmonary emboli, saddle embolus
Cardiovascular Diseases | Infectious Disease | Internal Medicine | Virus Diseases
The pathophysiology of coronavirus disease 2019 (COVID-19) involves multi-organ dysfunction, particularly involving the respiratory, cardiovascular and hematological systems. This dysfunction is partly due to systemic inflammation causing a wide array of pathological sequelae thus posing a significant challenge to management despite the advances in treatment made thus far. In this report, we present a COVID-19 patient who developed a transient complete heart block and was temporarily paced as a complication of a saddle pulmonary embolus (PE). The mechanism of complete heart block is unclear, may be related to strain, ischemia, or vagal response. We believe that this is a unique sequence of events in a COVID-19 patient and, to our knowledge, is the first of its kind to be reported.
Publisher or Conference
Ismail Z, Salabei JK, Stanger G, Asnake ZT, Frimer L, Smock A. Third-Degree Heart Block Associated With Saddle Pulmonary Embolism: A Rare Sequelae of COVID-19-Induced Hypercoagulable State. Cureus. 2021;13(7):e16246. doi:10.7759/cureus.16246