Adrenal Crisis Secondary to Influenza and Tetanus Vaccination in an Adult Without Known Adrenal Insufficiency: A Case of Autoimmune Adrenalitis

Authors

Shiwani Kamath, HCA HealthcareFollow
Jessica Khabra, HCA HealthcareFollow
Parth R. Desai MD, HCA HealthcareFollow
Johnathan Frunzi, HCA HealthcareFollow

Division

West Florida

Hospital

Medical Center of Trinity

Document Type

Case Report

Publication Date

7-11-2021

Keywords

adrenal crisis, post-vaccination, autoimmune adrenalitis, primary adrenal insufficiency, seasonal influenza vaccine, tetanus vaccine

Disciplines

Endocrine System Diseases | Internal Medicine

Abstract

Adrenal crisis (AC) is a rare but known life-threatening condition in patients with adrenal insufficiency (AI). We report the case of a 21-year-old without known AI who developed AC after routine vaccinations. Workup revealed that the patient had underlying, undiagnosed autoimmune adrenalitis. This is the first report of AC induced by influenza and diphtheria, tetanus, and acellular pertussis (DTaP) vaccinations in a patient without known AI.

Publisher or Conference

Cureus

Recommended Citation

Kamath S, Khabra JK, Desai P, Frunzi J. Adrenal Crisis Secondary to Influenza and Tetanus Vaccination in an Adult Without Known Adrenal Insufficiency: A Case of Autoimmune Adrenalitis. Cureus. 2021;13(7):e16312. doi:10.7759/cureus.16312