Cardio-oncology: Capecitabine Can Sometimes be Heatbreaking Capecitabine-Induced Takotsubo Cardiomyopathy Case Report and Literature Review.
Ocala Regional Medical Center
Capecitabine, Humans, Incidence, Neoplasms, Takotsubo Cardiomyopathy
Cardiology | Cardiovascular Diseases | Internal Medicine
Capecitabine has been more recognized for its cardiotoxicity with an incidence that varies widely. It demonstrates its toxicity in the forms of acute coronary syndrome, arrhythmias and, to a lesser extent, cardiomyopathy. There are several proposed theories including coronary vasospasm, endothelial injury, and oxidative stress. We present a case of capecitabine-induced cardiomyopathy in a patient with pancreatic cancer and mild coronary artery disease, and shed light on other cardio-toxic agents, their proposed mechanism of cardiotoxicity, and on cardiomyopathy in general.
Publisher or Conference
Current Problems in Cardiology
Abdelmaseih R, Blanco A, Abdelmasih R, et al. Cardio-oncology: Capecitabine Can Sometimes be Heatbreaking Capecitabine-Induced Takotsubo Cardiomyopathy Case Report and Literature Review. Curr Probl Cardiol. 2021;46(8):100854. doi:10.1016/j.cpcardiol.2021.100854