Subacute Thyroiditis Secondary to Moderna COVID-19 Vaccine: A Case Report of a Rare Manifestation


South Atlantic


Coliseum Northside Hospital

Document Type

Case Report

Publication Date



sars-cov-2, coronavirus infections, COVID-19, COVID-19 vaccines / adverse effects


Complex Mixtures | Infectious Disease | Internal Medicine | Virus Diseases


The SARS-CoV-2 led to a global pandemic, infecting millions of lives within only a short period of time. The symptoms of the disease vary with a subset of the population developing debilitating sequelae. Through the emergency use authorization (EUA), multiple vaccines have been released against the novel virus in record time. Long term and rare sequelae from the vaccine are poorly understood. DeQuervain’s subacute thyroiditis is a self-limiting and painful inflammation of the thyroid gland usually associated with viral infections. We report a rare case of subacute thyroiditis in a healthy 46-year-old woman presenting with a painful swelling in the neck after receiving the Moderna mRNA-1273 SARS-CoV-2 vaccine. We seek to elucidate a better understanding of rare vaccine side effects by documenting one of the first reported cases of subacute thyroiditis induced by the SARS-CoV-2 vaccine.

Publisher or Conference

Advances in Clinical Medical Research and Healthcare Delivery