A Case of Coombs-Negative Hemolytic Anemia Prompting Diagnosis of SARS‐CoV‐2
Brandon Regional Hospital
sars-cov-2, - hematology, coombs' negative, coronavirus disease 2019 (covid-19), hemolytic anaemia
Diagnosis | Internal Medicine | Virus Diseases
Case reports have discussed coronavirus disease of 2019 (COVID-19) patients presenting with hemolytic anemia, specifically with a positive direct antiglobulin test. However, Coombs-negative hemolytic anemia in COVID-19 patients has been rarely reported. We present an unusual case of Coombs-negative hemolytic anemia caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which responded with evidence-based COVID-19 treatments. We demonstrate the importance of considering SARS-CoV-2 as a cause of Coombs-negative hemolytic anemia, and we illustrate how treatment of the underlying COVID-19 illness, even if it is just supportive care, will help resolve the associated hemolysis.
Publisher or Conference
Neerukonda T, Moughabel W, Chen J, Patel D, Manji F. A Case of Coombs-Negative Hemolytic Anemia Prompting Diagnosis of SARS‐CoV‐2. Cureus. 2021;13(11):e20034. doi:10.7759/cureus.20034