A Case of Brugada Phenocopy in Adrenal Insufficiency-Related Pericarditis


Far West


MountainView Hospital

Document Type

Case Report

Publication Date



Brugada Phenocopy, Adrenal insufficiency, Pericarditis, Brugada Sign


Cardiovascular Diseases | Endocrine System Diseases | Internal Medicine


This is a report of a 27-year-old male with known history of Addison’s disease, noncompliant with medications, and hypothyroidism who presented with shortness of breath, nausea, vomiting, fever, and chest pain as well as Brugada sign seen on electrocardiogram. Echocardiogram revealed a moderate pericardial effusion and laboratory findings were suggestive of adrenal insufficiency. Patient was determined to have Type I Brugada phenocopy, which is a Brugada sign seen on EKG with a reversible cause. In this instance, the Brugada phenocopy was caused by adrenal insufficiency with associated pericarditis. Treatment with high-dose steroids led to resolution of both the pericardial effusion and Brugada sign, providing further evidence of Brugada phenocopy.

Publisher or Conference

Southwest Journal of Pulmonary and Critical Care