Outcomes of Endoscopic Retrograde Cholangio-pancreatography in Patients with Liver Transplant

Tsujung Yang
Achint Patel, HCA Healthcare
Rishita Pujari
Vincent P Okine
Lakshmi G Chirumamilla
Geethu Jnaneswaran
Athul Raj
Keji L Kwajok
Ruchir Goswami
Prakashkumar Maiyani
Maheshkumar Desai
Hardikkumar Shah
Matthew Grossman

Abstract

AIM OF THE STUDY: Biliary complications are the leading causes of morbidity and mortality after liver transplant (LT). However, national data on endoscopic retrograde cholangiopancreatography (ERCP) usage and outcomes in LT patients are lacking. Our study aims to identify the trends, outcomes, and predictors of ERCP and related complications in this patient subgroup.

MATERIAL AND METHODS: We derived our study cohort from the Nationwide Inpatient Sample (NIS) of the Healthcare Cost and Utilization Project (HCUP) between 2007 and 2017. LT patients were identified using ICD-9/10CM diagnosis codes and patients who underwent ERCP were identified by ICD-9/10-CM procedure codes. We utilized the Cochrane-Armitage trend test and multivariate logistic regression to analyze temporal trends, outcomes, and predictors.

RESULTS: A total of 372,814 hospitalizations occurred in LT patients between 2007 and 2017. ERCP was performed in 2.05% (

CONCLUSIONS: There has been an increase in ERCP procedures over the past decade among LT patients. Our study highlights the periprocedural complications and outcomes of ERCP in LT patients from a nationally representative dataset.