Exceedingly Rare Bilateral Synchronous Germ Cell Testicular Tumors With Different Histopathological Features


North Texas


Medical City Weatherford

Document Type

Case Report

Publication Date



bilateral synchronous testicular tumor, bilateral testicular cancer; bilateral testicular tumors, embryonal cell carcinoma, mixed germ cell tumor, primary choriocarcinoma, testicular seminoma, yolk sac tumor


Internal Medicine | Male Urogenital Diseases | Neoplasms


Bilateral synchronous testicular tumors are a relatively uncommon occurrence, especially when they involve germ cell tumors of different histology. In this context, we present a compelling case report of a male patient who was diagnosed with bilateral synchronous germ cell testicular tumors, with one being a seminoma and the other a non-seminomatous germ cell tumor (NSGCT). The coexistence of two distinct histological types, seminoma and NSGCT, necessitates a comprehensive diagnostic approach to accurately identify and characterize each tumor. This underscores the importance of clinical history, physical examination, imaging techniques, and histopathological analysis to establish an appropriate diagnosis. Careful consideration must be given to factors such as tumor stage, histological subtype, and individual patient characteristics to determine the most suitable treatment strategy. Treatment options may encompass a combination of surgery, chemotherapy, and radiation therapy, tailored to each tumor's specific characteristics and the patient's overall health. By highlighting this unique case, we aim to underscore the significance of meticulous evaluation and accurate diagnosis when confronted with bilateral synchronous testicular tumors of different histology.

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