North Texas GME Research Forum 2024



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North Texas


Medical City Arlington


Family Medicine

Document Type


Publication Date



multiple sclerosis, internuclear ophthalmoparesis, INO


Family Medicine | Immune System Diseases | Medicine and Health Sciences | Nervous System Diseases


Multiple Sclerosis is an inflammatory disorder of the central nervous system secondary to myelin degeneration. The disease is mediated by reactive lymphocytes where the spinal cord, brain and optic nerves are attacked. Diagnosis of MS is made clinically and confirmed via MRI with T2 hyperintensities. On presentation, a 26-year-old female with no significant past medical history presented with frequent headaches and blurry vision. There was right eye nystagmus on L lateral gaze with CN III deficits with absent medial rotation. MRI Head presented with a classic presentation of T2 hyperintensities in the subcortical and deep white matter. Further confirmed with NPO Igg antibodies. She was given a 3-day course of high dose Methylprednisolone with moderate symptom recovery.

Original Publisher

HCA Healthcare Graduate Medical Education

Case Report: Unilateral Internuclear Ophthalmoplegia as First Manifestation in Multiple Sclerosis



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