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vitamin d deficiency, fracture, pain, avitaminosis
Nutritional and Metabolic Diseases | Rheumatology
Vitamin D deficiency has been shown to contribute to the onset of musculoskeletal pain, headaches, and fatigue (1, 2). Deficient levels of calcium phosphate have been linked to musculoskeletal pain associated with vitamin D deficiency (3). Low levels of calcium phosphate may result in an inadequately mineralized bone matrix, and normalization of vitamin D levels should help to diminish symptoms of pain by correcting suboptimal mineralization of bone matrix (3). One prior study of patients who underwent orthopedic procedures (including treatment of vertebral compression fractures, Colle’s fractures, hip & knee arthroplasty, ligament repair, and meniscal repair), showed that 44% (n = 272) had evidence of vitamin D insufficiency (20-32 ng/mL) or deficiency (< 20 ng/mL) (4).
Korty, Theodore DO; Grunbaum, Adam DO; Baxa, Ken DO; and Oyesanmi, Olu, "Vitamin D Deficiency and Perceived Pain" (2020). West Florida Division Virtual Research Day. 35.