Acute Myeloid Leukemia Complicated by Hyperleukocytosis and Leukostasis in the Emergency Department

Division

West Florida

Hospital

Brandon Regional Hospital

Document Type

Case Report

Publication Date

6-2-2021

Keywords

acute myeloid leukemia, hyperleukocytosis, leukostasis, hematologic malignancies, blast crisis

Disciplines

Emergency Medicine | Hematology | Hemic and Lymphatic Diseases | Neoplasms | Oncology

Abstract

Acute myeloid leukemia (AML) and other hematologic malignancies can be complicated by hyperleukocytosis, which leads to an increased risk for other severe complications such as tumor lysis syndrome, disseminated intravascular coagulation (DIC), and leukostasis. In this report, we present a case of a 65-year-old female with newly diagnosed AML complicated by leukostasis. We briefly review the clinical significance as well as initial diagnostic and therapeutic considerations pertaining to hyperleukocytosis and its associated complications.

Publisher or Conference

Cureus

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