Intraparenchymal Hematoma With Significant Mass Effect Treated With Factor Eight Inhibitor Bypass Activity
Osceola Regional Medical Center
factor eight inhibitor bypass activity, prothrombin complex concentrate, andexanet alfa, fresh frozen plasma, intraparenchymal hematoma
Emergency Medicine | Hemic and Lymphatic Diseases
The authors present the case of an 80-year-old female with myelodysplastic syndrome treated with chemotherapy and apixaban, a direct oral anticoagulant who suffered an intracranial hemorrhage. She presented to the emergency department with altered mental status and was found to have a large intraparenchymal hematoma with a significant mass effect. Our patient was given FEIBA (Factor Eight Inhibitor Bypass Activity) to reverse the hemorrhage. Anticoagulant-related bleeding reversal strategies are discussed.
Publisher or Conference
Prasad S, Colon Figueroa P, Stead TS, Mangal RK, Ganti L. Intraparenchymal Hematoma With Significant Mass Effect Treated With Factor Eight Inhibitor Bypass Activity. Cureus. 2022;14(11):e31385. doi:10.7759/cureus.31385