An Adenoneuroendocrine Collision Tumor of the Pancreas: A Case Report

Division

Mountain

Hospital

Swedish Medical Center

Document Type

Case Report

Publication Date

10-26-2021

Keywords

Collision tumor, Pancreas, Pancreaticoduodenectomy, Pancreatic ductal adenocarcinoma, Neuroendocrine tumor

Disciplines

Endocrine System Diseases | Neoplasms | Surgery

Abstract

Collision tumors, specifically adenoneuroendocrine tumors of the pancreas, are rare. Here we present a 57-year-old female patient with neurofibromatosis who presented with 2 months of nausea, vomiting, and epigastric pain. Imaging and endoscopy revealed severe narrowing of the third portion of the duodenum and an incidental adrenal mass. She underwent an exploratory laparotomy, right adrenalectomy, and pancreaticoduodenectomy. Pathology revealed a 4.7 cm pT3bN2M0R1 peri-ampullary combined poorly differentiated carcinoma and grade 1 neuroendocrine tumor. Due to the small number of reported cases of mixed adenoneuroendocrine carcinoma of the pancreas, clinical behavior remains unclear and definitive management approaches have not been established.

Publisher or Conference

Journal of Current Surgery

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