An Adenoneuroendocrine Collision Tumor of the Pancreas: A Case Report
Swedish Medical Center
Collision tumor, Pancreas, Pancreaticoduodenectomy, Pancreatic ductal adenocarcinoma, Neuroendocrine tumor
Endocrine System Diseases | Neoplasms | Surgery
Collision tumors, specifically adenoneuroendocrine tumors of the pancreas, are rare. Here we present a 57-year-old female patient with neurofibromatosis who presented with 2 months of nausea, vomiting, and epigastric pain. Imaging and endoscopy revealed severe narrowing of the third portion of the duodenum and an incidental adrenal mass. She underwent an exploratory laparotomy, right adrenalectomy, and pancreaticoduodenectomy. Pathology revealed a 4.7 cm pT3bN2M0R1 peri-ampullary combined poorly differentiated carcinoma and grade 1 neuroendocrine tumor. Due to the small number of reported cases of mixed adenoneuroendocrine carcinoma of the pancreas, clinical behavior remains unclear and definitive management approaches have not been established.
Publisher or Conference
Journal of Current Surgery
Chung C, Darwish MB, McLaren PJ, et al. An Adenoneuroendocrine Collision Tumor of the Pancreas: A Case Report. J Curr Surg. 2021;11(4):87-96. doi: 10.14740/jcs440