Rapidly Progressing Moyamoya Syndrome Secondary to Meningovascular Neurosyphilis and Acquired Immunodeficiency Syndrome

Authors

Branden Wilson, HCA HealthcareFollow
Matthew Bear, HCA HealthcareFollow
Aswin Srinivasan, HCA HealthcareFollow
Khulood Rizvi, HCA HealthcareFollow
Samer Elfallal, HCA HealthcareFollow
Mohamad Ezzeldin, HCA HealthcareFollow

Division

Gulf Coast

Hospital

HCA Houston Healthcare Kingwood

Document Type

Case Report

Publication Date

7-2-2021

Keywords

moyamoya syndrome, vasculitis, neurosyphilis, human immunodeficiency virus, stroke

Disciplines

Bacterial Infections and Mycoses | Nervous System Diseases | Virus Diseases

Abstract

Moyamoya syndrome is a chronic and progressive narrowing of the arteries in the brain caused by different mechanisms than the genetic mutation that leads to moyamoya disease. It is characterized by the narrowing and/or closing of the carotid artery with a collateral circulation development around the blocked vessels to compensate for the ischemia. In this report, we present a unique case of moyamoya syndrome that developed over the course of a few months in a patient with new-onset strokes and seizures in the setting of late diagnosis of neurosyphilis and acquired immunodeficiency syndrome (AIDS). To our knowledge, moyamoya syndrome secondary to coinfection with AIDS and meningovascular neurosyphilis has only been reported once in the literature.

Publisher or Conference

Cureus

Recommended Citation

Wilson BC, Bear M, Srinivasan A, et al. Rapidly Progressing Moyamoya Syndrome Secondary to Meningovascular Neurosyphilis and Acquired Immunodeficiency Syndrome. Cureus. 2021;13(7):e16123. doi:10.7759/cureus.16123