Rare Complication of a Commonly Used Antihypertensive Agent: A Case of Hydralazine-Induced ANCA-Associated Vasculitis Presenting as Rapidly Progressive Glomerulonephritis

Authors

Kayle M. Warren, HCA HealthcareFollow
Khiem T. Vu, HCA HealthcareFollow
Karandeep Shergill, HCA HealthcareFollow
Brian Watson, HCA HealthcareFollow
Mohamed Faris, HCA HealthcareFollow

Division

South Atlantic

Hospital

Grand Strand Medical Center

Document Type

Case Report

Publication Date

2-7-2022

Keywords

drug‐induced vasculitis, hydralazine, pulmonary hemorrhage, pulmonary‐renal syndrome, rapidly progressive glomerulonephritis

Disciplines

Cardiovascular Diseases | Internal Medicine

Abstract

Hydralazine-induced ANCA-associated vasculitis is a rare clinical entity, with complications including rapidly progressive glomerulonephritis, pulmonary hemorrhage, and pulmonary-renal syndrome. We present this case to highlight the clinical features that support this challenging diagnosis and to emphasize the importance of prompt recognition and aggressive intervention given its significant morbidity and mortality.

Publisher or Conference

Clinical Case Reports

Recommended Citation

Warren K, Vu K, Shergill K, Watson B, Faris M. Rare complication of a commonly used antihypertensive agent: A case of hydralazine-induced ANCA-associated vasculitis presenting as rapidly progressive glomerulonephritis. Clin Case Rep. 2022;10(2):e05411. Published 2022 Feb 7. doi:10.1002/ccr3.5411