The First Documented Case of Marchiafava-Bignami Disease with Concurrent Bilateral Deep Vein Thrombosis

Division

East Florida

Hospital

Westside Regional Medical Center

Document Type

Case Report

Publication Date

2-23-2022

Keywords

Marchiafava-Bignami, Bilateral Deep Vein Thrombosis, Neurology, Cardiovascular System

Disciplines

Cardiovascular Diseases | Internal Medicine | Nervous System Diseases

Abstract

Marchiafava-Bignami Disease (MBD) presents as a rare neurological disease characterized by demyelination and necrosis in the corpus callosum. Most MBD cases are secondary to severe alcohol abuse and hypovitaminosis. MRI and other forms of neuroradiological imaging is necessary to confirm the diagnosis. We herein present an atypical case of a MBD and history of alcohol abuse who developed deep vein thrombosis in his bilateral lower extremities. This novel case represents the first documented report of MBD with concurrent DVT. Furthermore, we hypothesize that DVT may be a long-term complication associated with MBD.

Publisher or Conference

Journal of Neurology Research Reviews & Reports

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