A Case of Bilateral Cerebral Venous Sinus Thrombosis: More Than Meets the Eye

Division

Far West

Hospital

MountainView Hospital

Document Type

Case Report

Publication Date

7-16-2022

Keywords

hereditary protein s deficiency, cerebral venous sinus thrombosis (cvst), covid-19, plasminogen activator inhibitor-1 (pai-1), jak 2 mutation

Disciplines

Cardiovascular Diseases | Hematology | Internal Medicine | Nervous System Diseases

Abstract

Cerebral venous sinus thrombosis (CVST) is a rare etiology of stroke that results from inherited and/or acquired conditions, which can present in a variety of symptoms. CVST in the setting of the 2019 coronavirus disease (COVID-19) has rarely been observed. Herein, we present the case of a 32-year-old female with a recent history of COVID-19 subsequently found to have CVST involving bilateral transverse sinuses. Further workup demonstrated several hypercoagulable conditions, which were likely exacerbated by the viral infection. This case demonstrates an atypical outcome for young, COVID-19-positive patients, which emphasizes the importance of diligence when examining symptomatic patients with a history of COVID-19 infection. The patient was treated with apixaban therapy with radiographic resolution of bilateral CVST and improved vision.

Publisher or Conference

Cureus

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