Association of Dementia and Patient Outcomes Among COVID-19 Patients: A Multi-Center Retrospective Case-Control Study
TriStar Centennial Medical Center
COVID-19, baseline characteristics, dementia, intensive care unit (ICU), mortality
Critical Care | Internal Medicine | Nervous System Diseases | Psychiatry | Psychiatry and Psychology | Virus Diseases
BACKGROUND: We conducted a retrospective cohort study on COVID-19 patients with and without dementia by extracting data from the HCA Healthcare Enterprise Data Warehouse between January-September 2020.
AIMS: To describe the role of patients' baseline characteristics specifically dementia in determining overall health outcomes in COVID-19 patients.
METHODS: We grouped in-patients who had ICD-10 codes for dementia (DM) with age and gender-matched (1:2) patients without dementia (ND). Our primary outcome variables were in-hospital mortality, length of stay, Intensive Care Unit (ICU) admission, ICU-free days, mechanical ventilation (MV) use, MV-free days and 90-day re-admission.
RESULTS: Matching provided similar age and sex in DM and ND groups. BMI (median, 25.8 vs. 27.6) and proportion of patients who had smoked (23.3 vs. 31.3%) were lower in DM than in ND patients. The median (IQR) Elixhauser Comorbidity Index was higher in dementia patients 7 (5-10) vs. 5 (3-7,
CONCLUSIONS: Our data showed that COVID-19 patients with dementia did not fare substantially worse, but in fact, fared better when certain metrics were considered.
Publisher or Conference
Frontiers in Medicine: Geriatric Medicine
Vekaria PH, Syed A, Anderson J, et al. Association of dementia and patient outcomes among COVID-19 patients: A multi-center retrospective case-control study. Front Med (Lausanne). 2022;9:1050747. doi:10.3389/fmed.2022.1050747