SARS-CoV-2 Infection Precipitates the Discovery of Underlying Liver Disease: A Case Report

Division

Far West

Hospital

MountainView Hospital

Document Type

Case Report

Publication Date

4-19-2023

Keywords

a1at, alpha-1-antitrypsin deficiency, covid-19, gastroenterology and hepatology, hepatology, transaminitis

Disciplines

Digestive System Diseases | Gastroenterology | Internal Medicine | Virus Diseases

Abstract

Since the onset of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, numerous sequelae of this devastating virus have come to light. One organ known to be impacted by SARS-CoV-2 is the liver, as many SARS-CoV-2 patients demonstrate elevated liver enzymes on routine laboratory tests. In this case report, we present a patient with SARS-CoV-2 whose liver enzymes remained persistently elevated throughout his hospitalization. Due to the duration of his elevated liver enzymes, etiologies outside of SARS-CoV-2 were explored. This workup revealed that the patient had alpha-1 antitrypsin (A1AT) deficiency. Thus, this case serves to remind clinicians to continue investigating lab abnormalities despite a presumed etiology, such as SARS-CoV-2, so as not to miss the presentation of new diagnoses.

Publisher or Conference

Cureus

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