SARS-CoV-2 Infection Precipitates the Discovery of Underlying Liver Disease: A Case Report
a1at, alpha-1-antitrypsin deficiency, covid-19, gastroenterology and hepatology, hepatology, transaminitis
Digestive System Diseases | Gastroenterology | Internal Medicine | Virus Diseases
Since the onset of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, numerous sequelae of this devastating virus have come to light. One organ known to be impacted by SARS-CoV-2 is the liver, as many SARS-CoV-2 patients demonstrate elevated liver enzymes on routine laboratory tests. In this case report, we present a patient with SARS-CoV-2 whose liver enzymes remained persistently elevated throughout his hospitalization. Due to the duration of his elevated liver enzymes, etiologies outside of SARS-CoV-2 were explored. This workup revealed that the patient had alpha-1 antitrypsin (A1AT) deficiency. Thus, this case serves to remind clinicians to continue investigating lab abnormalities despite a presumed etiology, such as SARS-CoV-2, so as not to miss the presentation of new diagnoses.
Publisher or Conference
Diaz V, Benge E, Brockway M, Truman W, Ahmed B. SARS-CoV-2 Infection Precipitates the Discovery of Underlying Liver Disease: A Case Report. Cureus. 2023;15(4):e37811. doi:10.7759/cureus.37811