Ultrasound-Accelerated Catheter-Directed Thrombolysis

Division

North Florida

Hospital

Ocala Regional Medical Center

Document Type

Review Article

Publication Date

6-1-2023

Keywords

Catheter-directed thrombolysis, Deep venous thrombosis, Embolectomy, Pulmonary embolism, Venous thromboembolism

Disciplines

Cardiovascular Diseases | Internal Medicine

Abstract

Venous thromboembolism is a very common presentation in the hospital setting. In patients with high-risk pulmonary embolism (PE) or PE and hemodynamic instability, systemic thrombolytic treatment is generally indicated. In those with contraindications to systemic thrombolysis, catheter-directed local thrombolytic therapy and surgical embolectomy are currently considered. In particular, catheter-directed thrombolysis (CDT) is a drug delivery system coupling the endovascular drug administration nearby in the thrombus and the local facilitating effect of ultrasounds. The applications of CDT are currently debated. Here we provide a systematic review of the clinical utilization of CDT.

Publisher or Conference

Cardiology Research

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