The Importance of Excisional Biopsy in Nodular Lymphocyte-Predominant Hodgkin's Lymphoma

Division

South Atlantic

Hospital

Grand Strand Medical Center

Document Type

Case Report

Publication Date

6-10-2023

Keywords

excisional tissue biopsy, hematology-oncology, hodgkin’s lymphoma, nodular lymphocyte-predominant hodgkin’s lymphoma, non-hodgkin’s lymphoma, supraclavicular lymphadenopathy

Disciplines

Hemic and Lymphatic Diseases | Internal Medicine | Neoplasms

Abstract

Hodgkin's lymphoma (HL) is a malignancy that is typically B-cell in origin. HL can be further classified into classical HL and nodular lymphocyte-predominant HL (NLPHL). NLPHL is a rare lymphoma. It commonly presents locally with palpable firm lymphadenopathy or mediastinal mass seen on chest imaging. Some patients may have B symptoms (fever, night sweats, and unintentional weight loss), splenomegaly, and hepatomegaly. We describe a case of NLPHL in a 32-year-old male with classical findings of this rare class of HL.

Publisher or Conference

Cureus

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