Management of Cardiovascular Implantable Electronic Device Infection Utilizing a Multidisciplinary Team: A Retrospective Cohort Study
Division
West Florida
Hospital
Medical Center of Trinity
Document Type
Manuscript
Publication Date
3-10-2025
Keywords
cardiac implantable electronic device extraction, cardiac implantable electronic device infections, endocarditis teams, lead management teams, multidisciplinary teams
Disciplines
Bacterial Infections and Mycoses | Cardiovascular Diseases | Internal Medicine | Medicine and Health Sciences
Abstract
BACKGROUND: Significant numbers of cardiac implantable electronic devices are placed in the United States, and infection can be a severe consequence of implantation. Despite guideline recommendations and data demonstrating that lead extraction improves mortality for patients with device infection, rates of lead removal are lower than guideline recommendations. We report the outcomes associated with management of suspected cardiac implantable electronic device infections by a multidisciplinary team.
METHODS: Patient cases were identified from an institutional multidisciplinary endocarditis team registry in a single-center retrospective study. Demographic, treatment, and outcomes data were recorded by study investigators.
RESULTS: Between September 7, 2021, and February 1, 2024, 80 consecutive patients with suspected cardiac implantable electronic device infections were identified. Fifty-four (67.5%) patients, including 27/35 (77.1%) with definitive device infection/endocarditis and 30/30 (100%) with pocket infections, underwent device removal at a median of 3 days after admission to the authors' institution. In-hospital and 90-day mortality was numerically lower in patients who underwent device removal compared with those who did not (13% vs 19.2%;
CONCLUSIONS: The use of a multidisciplinary team for management of suspected cardiac implantable electronic device infections was associated with high rates of expedient device extraction and relatively low rates of device reimplantation. One-year mortality was lower in patients who underwent device extraction.
Publisher or Conference
Open Forum Infectious Diseases
Recommended Citation
Hall E, Collis B, Alnabelsi T, et al. Management of Cardiovascular Implantable Electronic Device Infection Utilizing a Multidisciplinary Team: A Retrospective Cohort Study. Open Forum Infect Dis. 2025;12(4):ofaf148. Published 2025 Mar 10. doi:10.1093/ofid/ofaf148