Autoimmune Pancreatitis Not Otherwise Specified (AIP-NOS): The Importance of Gastroenterology Consultation When Clinical Findings Are Concerning for Pancreatic Cancer

Division

South Atlantic

Hospital

Memorial Health University Medical Center

Document Type

Case Report

Publication Date

9-9-2025

Keywords

autoimmune pancreatitis not otherwise specified, biliary strictures, obstructive jaundice, pancreatic neoplasms

Disciplines

Digestive System Diseases | Gastroenterology | Immune System Diseases | Internal Medicine | Medicine and Health Sciences | Pathology | Radiology

Abstract

Introduction: Autoimmune pancreatitis (AIP) and pancreatic cancer are top differentials of obstructive jaundice originating from the pancreas. Case Description/Methods: The patient's findings were concerning for malignant biliary obstruction, but a thorough workup determined that the patient had AIP-NOS. She underwent EBS and was discharged on a steroid taper. Follow-up demonstrated complete resolution of symptoms, laboratory markers, and imaging. Conclusion: Adequate pancreatic tissue is not always obtained with 22-gauge needles. Biliary stenting is justifiable in AIP with significant hyperbilirubinemia. It is important to consider AIP for with a pancreatic head mass and obstructive jaundice to optimize outcome.

Publisher or Conference

Case Reports in Gastrointestinal Medicine

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