Secondary Syphilis With Isolated Ocular Syphilis and Superimposed Corneal Abrasion: A Case Report

Division

West Florida

Hospital

Citrus Memorial Hospital

Document Type

Case Report

Publication Date

9-14-2025

Keywords

corneal abrasion, neurosyphilis, ocular syphilis, secondary syphilis, syphilis, syphilitic uveitis

Disciplines

Bacterial Infections and Mycoses | Eye Diseases | Internal Medicine | Medicine and Health Sciences

Abstract

Ocular syphilis is a rare and easily preventable disease that can progress quickly to permanent blindness. Symptoms can mimic other ocular pathologies and further delay diagnosis. The incidence of syphilis continues to rise each year and represents significant morbidity in high-risk communities. In this case, the patient presented with unilateral blindness, uveitis, and a maculopapular rash on the lower extremities. Initially, she was found to have a corneal abrasion, leading to a missed diagnosis of ocular syphilis and delayed treatment. This case brings awareness to ocular syphilis as a key diagnosis to consider in a patient with unilateral ocular pathology that is refractory to treatment. Quick diagnosis is essential to prevent progression to permanent blindness.

Publisher or Conference

Cureus

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