Cancer, Glomus (Glomangioma)

Division

East Florida

Hospital

Aventura Hospital and Medical Center

Document Type

Review Article

Publication Date

4-26-2020

Keywords

glomus tumor, glomuvenous malformations, GVM, neoplasms, vascular tissue neoplasms

Disciplines

Internal Medicine | Neoplasms | Skin and Connective Tissue Diseases

Abstract

Glomangiomas, or glomuvenous malformations (GVM), are rare cutaneous venous malformations that show glomus cells (undifferentiated smooth muscle cells, which are thermoregulatory units), along with venous system in histology. Glomus cells specialized smooth muscle cells that regulate the temperature in the body. Masson first described glomangiomas and Papoff further extensively studied. There are three types of glomus tumors, classified based on its dominant component: 1. Solid: mainly glomus cells. 2. Glomangioma: mainly blood vessels. 3. Glomangiomyoma: mainly smooth muscle cells. Glomangimyomas are further divided into (a) regional, (b) disseminated, and (c) congenital plaque-like. Glomangiomas usually present in multiples, often at birth or during childhood, and they do not involve the subungual region. A majority of glomangiomas are benign, although malignant cases have also been reported. Rarely seen, the disseminated type distributes throughout the body.

Publisher or Conference

StatPearls

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