North Texas Research Forum 2024

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Division

North Texas

Hospital

Medical City Weatherford

Specialty

Internal Medicine

Document Type

Poster

Publication Date

2024

Keywords

bariatric surgery, glucagon-like peptide (GLP-1) receptor agonists

Disciplines

Internal Medicine | Medicine and Health Sciences | Surgical Procedures, Operative

Abstract

Glucagon-like peptide receptor agonists (GLP-1 RA) are FDA-approved medications for the treatment of type 2 diabetes mellitus, and obesity, and are also beneficial in cardiovascular risk reduction. However, due to known GLP-1 RA adverse effects, notably delayed gastric emptying, the ASA has implemented GLP-1RA guidelines aiming to minimize potential complications related to GLP-1 RA use in patients undergoing procedures requiring general anesthesia. With the ever-increasing number of patients being prescribed GLP-1 RAs, more research needs to be conducted to investigate their potential impact in other areas of healthcare. This retrospective study aims to compare surgical outcomes before and following the implementation of the ASA guidelines to determine the role of GLP-1RAs in these outcomes. Using data provided by the National Bariatric Data Bank for Medical City Fort Worth, we will compare the outcomes of patients who underwent surgical procedures from 7/1/22-10/31/22 to those from 7/1/23-10/31/23. We will compare the outcomes of each group in regard, to peri- and post-operative outcomes, length of stay, and prior risk factors. We will then determine the number of patients on GLP-1RA therapy in each group and compare the outcomes. We anticipate a significant difference (P<.05) in the number of surgical complications and peri- and post-operative events before implementation of the ASA GLP-1RA guidelines compared to those following. Additionally, we anticipate a significant difference in the peri- and postoperative complications in those patients on GLP-1RAs, whose medication was held before the procedure following the new ASA guidelines. We anticipate a significant difference in peri- and postoperative complications in patients with severe diabetes and disease sequelae, before and following the implementation of the ASA GLP-1 guidelines to hold GLP-1RA therapy prior to procedures requiring general anesthesia.

Original Publisher

HCA Healthcare Graduate Medical Education

Association of Glucagon-Like Peptide-1 Receptor Agonist Treatment with Perioperative and Postoperative Complications in Patients Undergoing Elective Bariatric Surgery

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