A Retrospective Study on the Effect of RAAS Pathway Inhibitors at Decreasing the Risk of Acute Coronary Syndrome in Hypertensive Patients with Rheumatoid Arthritis as Compared to Other Antihypertensives

Authors

Yousuf Sherwani, HCA HealthcareFollow
Asad Risvi
Senthil Thambidorai, HCA HealthcareFollow

Files

Division

North Texas

Hospital

Medical City Arlington

Specialty

Internal Medicine

Document Type

Poster

Publication Date

2024

Keywords

acute coronary syndrome, rheumatoid arthritis, RAAS pathway inhibitors

Disciplines

Cardiology | Immune System Diseases | Internal Medicine | Medicine and Health Sciences | Musculoskeletal Diseases

Abstract

Rheumatoid arthritis (RA) is a chronic multi-system inflammatory disease of which is characterized by articular and extra-articular involvement. Patients with RA have a higher risk of mortality when compared with the general population, which is due predominantly to increased cardiovascular disease. Due to the higher incidence of CVD and MI in RA patients it has been postulated that enhanced systemic inflammation plays an important role in the pathogenesis of CVD in RA patients. Previous studies have shown that ant inflammatory medication such as systemic steroids and immune blockers have been shown to decrease the risk of MI in patients with rheumatoid arthritis. Our results found that there was a decrease in the risk of ACS In patients taking ace inhibitors however the p value was not sustain due to a lack of sample size.

Original Publisher

HCA Healthcare Graduate Medical Education

Recommended Citation

Sherwani, Yousuf; Risvi, Asad; and Thambidorai, Senthil, "A Retrospective Study on the Effect of RAAS Pathway Inhibitors at Decreasing the Risk of Acute Coronary Syndrome in Hypertensive Patients with Rheumatoid Arthritis as Compared to Other Antihypertensives" (2024). North Texas GME Research Forum 2024. 20.
https://scholarlycommons.hcahealthcare.com/northtexas2024/20