Complications Rates After Total Knee Arthroplasty in Patients With Peripheral Vascular Disease

Division

North Texas

Hospital

Medical City Denton

Document Type

Manuscript

Publication Date

5-11-2026

Keywords

total knee arthroplasty, TKA, peripheral vascular disease

Disciplines

Medicine and Health Sciences | Orthopedics

Abstract

BACKGROUND: As the population continues to grow and age, the number of projected total knee arthroplasty (TKA) procedures is expected to grow substantially by 2030. This retrospective study reviews peripheral vascular disease (PVD) and correlations between postoperative complications in patients undergoing TKA with concomitant PVD.

METHODS: Patient de-identified data was queried using an enterprise-wide database from January 2016-July 2023. 11,831 initial patients over the age of 50 that had undergone TKA were found and 446 patients were removed due to missing demographic information leaving 11,385 patients for analysis. Patients were then separated into two cohorts: group 1 underwent TKA with an ICD-10 documented diagnosis of PVD and group 2 that underwent TKA without a concomitant diagnosis of PVD. Chi-squared analysis was then performed to identify statistical differences in postoperative complications between the two cohorts.

RESULTS: Group 1 had developed a surgical site infection (SSI) in 5.21% compared to 4.66% in Group 2 (p = 0.28). Arthrofibrosis developed in 0.85% in Group 1 and 0.78% in Group 2 (p = 0.71). The mortality rate after TKA was not significantly different between the two groups (p = 0.31). Venous thromboembolism (VTE) was present in 10.06% in Group 1 and 5.34% of patients in Group 2 (p < 0.0001). New arrhythmia, pneumonia, delirium, and UTI were all increased in Group 1 patients (p < 0.001). Patients with PVD (Group 1) had a statistically significant longer length of stay compared to patients without PVD (Group 2), controlling for age, sex, and race (IRR = 1.31, p < 0.001).

CONCLUSIONS: The results of this retrospective study demonstrate an increased length of stay, increase in medical complications, and a statistically significant difference in VTE rates in patients with a history of PVD undergoing TKA as compared to those without. There was no significant difference in arthrofibrosis, SSI, and mortality in patients receiving TKA with a history of PVD compared to without PVD.

Publisher or Conference

The Journal of Knee Surgery

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