Exacerbation of Fragile X-associated Tremor/Ataxia Syndrome in the Context of COVID-19 Infection: A Case Report.

Division

Far West

Hospital

MountainView Hospital

Document Type

Case Report

Publication Date

9-23-2024

Keywords

cerebellar ataxia, covid-19, fmr1 gene, fragile x-associated tremor/ataxia syndrome, fxtas (fragile x-associated tremor/ataxia syndrome), neurodegenerative disorder

Disciplines

Congenital, Hereditary, and Neonatal Diseases and Abnormalities | Medicine and Health Sciences | Nervous System Diseases | Rehabilitation and Therapy

Abstract

Fragile X-associated tremor/ataxia syndrome (FXTAS) is a late-onset neurodegenerative disorder affecting premutation carriers of the FMR1 gene. This case report presents a 65-year-old male who was diagnosed with FXTAS after presenting with an acute exacerbation of neurological symptoms in the setting of a COVID-19 infection. The case highlights the potential for viral infections to trigger the worsening of FXTAS symptoms and emphasizes the importance of comprehensive evaluation in such scenarios.

Publisher or Conference

Cureus

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