An Atypical Presentation of Neuroleptic Malignant Syndrome

Authors

Rudy Forte, HCA HealthcareFollow
Shiwani Kamath, HCA HealthcareFollow
Debra Angelo, HCA HealthcareFollow
Johnathan Frunzi, HCA HealthcareFollow

Files

Division

West Florida

Hospital

Medical Center of Trinity

Specialty

Internal Medicine

Document Type

Poster

Publication Date

5-2020

Keywords

Neuroleptic malignant syndrome; Atypical NMS; Aripiprazole induced NMS; Afebrile NMS

Disciplines

Internal Medicine | Nervous System Diseases | Psychiatry

Abstract

Neuroleptic Malignant Syndrome (NMS) is a rare, but potentially life threatening condition associated with dopamine blockade, particularly first-generation antipsychotics. The complex pathophysiology of NMS remains somewhat unclear and debatable as the symptoms are not fully explained by dopamine blockade alone.¹ D2 dopamine receptor antagonism remains responsible for most cases of NMS, however a few cases have been reported in which little to no D2 blockade activity was present.¹

This poster is about an atypical presentation of NMS.

Recommended Citation

Forte, Rudy; Kamath, Shiwani; Angelo, Debra; and Frunzi, Johnathan, "An Atypical Presentation of Neuroleptic Malignant Syndrome" (2020). West Florida Division GME Research Day 2020. 1.
https://scholarlycommons.hcahealthcare.com/westflorida2020/1