Keeping It Simple: A Case Report on Atomized Intranasal 1% Lidocaine as an Effective Treatment for Pain Crisis Due to Trigeminal Neuralgia

Division

North Florida

Hospital

Osceola Regional Medical Center

Document Type

Case Report

Publication Date

11-24-2025

Keywords

chronic pain, emergency medicine, intranasal, lidocaine, trigeminal neuralgia

Disciplines

Emergency Medicine | Nervous System Diseases | Stomatognathic Diseases

Abstract

Trigeminal neuralgia (TN) is a chronic pain disorder characterized by recurrent attacks of sudden facial pain. Unfortunately, there are few options to adequately prevent attacks of TN and even fewer options for rescue therapy during acute episodes. Successful treatment of TN pain with the readily available 1% formulation, typically used for local anesthesia, has not yet been demonstrated. We present a case report of a 37-year-old male patient who presented to the emergency department with severe, debilitating TN pain and achieved significant relief within 20 minutes of intranasal (IN) atomized 1% lidocaine.

Publisher or Conference

Cureus

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