Cauda Equina Syndrome as the Initial Presentation of Concurrent Plasmacytoma and Multiple Myeloma

Division

West Florida

Hospital

Brandon Regional Hospital

Document Type

Case Report

Publication Date

1-24-2021

Keywords

multiple myeloma, plasmacytoma, back pain, cauda equina syndrome, spinal cord injury

Disciplines

Hematology | Neoplasms | Neurosurgery | Oncology

Abstract

Multiple myeloma is a hematological malignancy characterized by an abnormal proliferation of monoclonal plasma cells. In some occurrences, plasma cell proliferation results in a solitary lesion (solitary bone plasmacytoma or extramedullary plasmacytoma with minimal bone marrow involvement). Approximately 50% of patients with solitary plasmacytoma develop multiple myeloma within 10 years after the initial diagnosis. While back pain and compression fractures are commonly described presentations of multiple myeloma and plasmacytoma, cauda equina syndrome related to plasma cell infiltration is rare and clinical guidelines are limited. Herein, we present a rare case of a woman with acute cauda equina syndrome (CES) secondary to solitary bone plasmacytoma and multiple myeloma.

Publisher or Conference

Cureus

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