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Scholarly Commons > HCA Healthcare Journal > Vol. 4 > Iss. 6 (2023)

 

Keywords

Candidiasis; invasive; Candida glabrata; cervical spondylodiscitis; discitis; spondylitis

Disciplines

Infectious Disease | Internal Medicine | Neurosurgery

Abstract

Introduction

Invasive candidiasis can lead to numerous life-threatening sequelae. Candida glabrata is the second-most common causative species of invasive candidiasis. This species possesses a high risk for persistent infection and candidemia. An uncommon complication of invasive candidiasis is spondylodiscitis and can rarely affect the cervical spine.

Case Presentation

The patient is a female in her late 50s with a complex medical history inclusive of chronic obstructive pulmonary disease, chronic pain, multiple abdominal surgeries, prolonged intensive care unit admission, and administration of total parenteral nutrition and broad-spectrum antibiotics who presented with complaints of worsening neck pain. She was last hospitalized 3 months prior and found to have C glabrata fungemia but was nonadherent to antifungal therapy.

She was found to have advanced C5-6 spondylodiscitis and an epidural abscess. Her surgical cultures grew C glabrata. Despite surgical intervention and antimicrobial therapy, she clinically deteriorated and acquired septic shock with multiorgan failure.

Conclusion

This is a rare case of cervical spondylodiscitis caused by a deep-seated C glabrata infection.

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