Keywords
immunoglobulin A; IgA; corticosteroids; prednisone; methylprednisolone; drug therapy; adults; case reports
Disciplines
Internal Medicine | Rheumatology
Abstract
Background
Immunoglobulin A (IgA) vasculitis is common in children and typically resolves spontaneously. However, when presenting in adults, it is more likely to be severe and recurrent.
Case Presentation
We present the case of a 19-year-old female patient with recurrent steroid-dependent IgA vasculitis. She had a history of a prolonged episode of IgA vasculitis in childhood. She presented to our hospital with proteinuria and a painful, palpable purpuric rash on her bilateral lower extremities. She was treated with high-dose intravenous steroids. When steroids were tapered, the patient had a recurrence of her painful rash. Over several months, she developed steroid-induced hyperglycemia and worsening proteinuria.
Conclusion
Recent studies have shown that corticosteroids have limited effect on long-term outcomes in IgA vasculitis, but steroid-sparing agents have potential for the treatment of recurrent steroid-dependent IgA vasculitis.
Recommended Citation
Berrett, Hannah; Gohil, Shivangi; Kurian, Rebecca; and Neyman, Patricia
(2024)
"Steroid-Dependent Recurrent IgA Vasculitis in a 19-Year-Old Woman,"
HCA Healthcare Journal of Medicine: Vol. 5:
Iss.
4, Article 10.
DOI: 10.36518/2689-0216.1660
Available at:
https://scholarlycommons.hcahealthcare.com/hcahealthcarejournal/vol5/iss4/10
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