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Scholarly Commons > HCA Healthcare Journal > Vol. 6 > Iss. 6 (2025)

 

Keywords

B-cell lymphoma; hemic and lymphatic diseases; neoplasms; cutaneous B-cell lymphomas; aged

Disciplines

Hemic and Lymphatic Diseases

Abstract

A man over the age of 89 presented with 2 violaceous, ulcerated plaques on his left lower leg, which developed over a 4-month period following a fall. The patient reported the initial formation of a solitary lump, which gradually enlarged and began bleeding a few weeks before his clinic visit. A histological examination of 2 biopsy samples revealed a dermal proliferation of large, severely atypical lymphoid cells with mitotic figures. Immunohistochemistry showed positivity for CD20, Bcl2, Bcl6, and MUM1, with cytokeratin 20 (CK20) negativity and a high percentage (80%-90%) of C-MYC positivity, which was consistent with a primary cutaneous diffuse large B-cell lymphoma (PCDLBC-LT). Given the findings, the patient was referred to oncology for further management.

Erratum

Patient demographic information was corrected.

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