Juvenile-Type Granulosa Cell Tumor in Pregnancy Presenting as a Ruptured Abdominal Mass
granulosa cell tumor; sex cord-gonadal stromal tumors; ovarian neoplasms; ovarian diseases; pregnancy; pregnancy complications
Obstetrics and Gynecology | Oncology | Surgery
Granulosa cell tumors (GCTs) are part of the sex cord-stromal tumors occurring with a rare incidence rate that only makes up about 2-5% of all ovarian malignancies.
A 28-year-old woman, gravida 2, para 1, presented with a juvenile-type granulosa cell tumor at 31 weeks gestation, which appeared as a rapidly growing mass with rupture. She underwent an exploratory laparotomy with unilateral salpingo-oophorectomy, and consequently had a successful vaginal delivery. Post-operatively she was treated with paclitaxel and carboplatin chemotherapy regimen with no evidence of recurrence after one year.
Radical surgical management is recommended for these tumors due to the high recurrence rate, but more conservative surgical options may be considered based on the fertility goals of the patient.
Mogor, Odinaka; Feinstein, Steven; Friedman, Glen; Saldivar, Jose Salvador; and Mendez, Melissa
"Juvenile-Type Granulosa Cell Tumor in Pregnancy Presenting as a Ruptured Abdominal Mass,"
HCA Healthcare Journal of Medicine: Vol. 4:
1, Article 7.
Available at: https://scholarlycommons.hcahealthcare.com/hcahealthcarejournal/vol4/iss1/7
Obstetrics and Gynecology Commons, Oncology Commons, Surgery Commons